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Aetna's struggles and a goodwill impairment charge have challenged the company this year.
The financial challenges are linked to a lawsuit charging the PBM with filing more than 3.3 million false claims from 2010 to 2018.
Aetna saw its medical benefits ratio increase months after CVS announced it would exit the ACA individual market due to struggling performance.
The AGs say CVS Health charged these programs higher prices than they offered to the general public for the same drugs.
The amount is based on Walgreens' ability to pay, and if sold, the company would owe an additional $50M, DOJ says.
Walgreens was accused of engaging in a "systematic and routine waiver of patient copayments."
The lawsuit says Walgreens sought reimbursement for the prescriptions from various federal healthcare programs.
A federal investigation uncovered a scheme to steer vendor contracts to medical supply companies in exchange for cash.
The charges are unlawful distribution of about 70 million opioid pills and 30 million doses of other prescription drugs.
Various forms of a potential separation are reportedly under consideration, though specifics remain unclear.