In early October the U.S. Preventive Services Task Force, an advisory panel that helps inform the government on preventive healthcare, downgrade its recommendation on the PSA test for prostate cancer screening to a grade of D. It recommended doctors not routinely prescribe the test because "there is moderate or high certainty that the service has no net benefit or that the harms outweigh the benefits."
Not surprisingly, the news was greeted by howls of protest from many corners of the healthcare community as well as those who have had the test, successfully treated their cancer and have gone on to live their lives.
If you accept the fact that in the future of healthcare, you can't have and simultaneously pay for everything, then the debate around the PSA and its relative value is as good a place to start as any.